Research Vault

Health & human behavior · Research feature

Under the
Influence

Six questions about addiction, the experiences around it, and life in recovery.

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Addiction research asks several connected questions: what a pattern of substance use looks like, why stopping can be difficult, what families experience, and what helps people recover. Personal accounts add another perspective, including the place of faith.

01Understanding the terms

What does an addiction pattern look like?

Reading about addiction can bring up a personal question: “Does this sound like me?” A phrase often used in that conversation is “addictive personality.” It is an informal label, not a psychiatric diagnosis. It does not describe a single, fixed kind of person. Cleveland Clinic, 2023 ↗

Personality can still be part of the research. NIAAA includes impulsivity among the tendencies involved in risk for alcohol use disorder. But risk also involves biology, experiences, and environment. NIDA emphasizes that no single factor determines whether someone develops addiction. NIAAA & NIDA ↗

Clinical descriptions of substance use disorders focus on patterns of use and their effects on daily life. Three ideas help explain some of those descriptions: difficulty controlling use, other activities being displaced, and continuing despite harm. American Psychiatric Association ↗

The expandable examples below concern alcohol. Each pairs a fictional thought with an imagined pattern of behavior. They explain concepts; they are not a checklist or an assessment of the reader.

Control — difficulty keeping a limit

Fictional thought: “I'll stop after this one.”

In this example, a person repeatedly drinks more than intended, despite efforts to keep a limit.

Priority — other activities lose space

Fictional thought: “I'd rather stay home and drink.”

In this example, drinking and recovering from its effects repeatedly take the place of activities the person used to value.

Impact — use continues despite problems

Fictional thought: “I know it's causing problems, but I still want to drink.”

In this example, drinking continues despite recurring relationship problems that alcohol causes or makes worse.

These teaching examples draw on NIAAA's descriptions of alcohol use disorder. They do not cover every clinical feature, and the thoughts themselves are not diagnostic signs. NIAAA: descriptions and context ↗

A familiar thought or one incident does not establish a disorder. An individual assessment belongs with a qualified healthcare professional who can consider the wider pattern and circumstances. A reader with concerns can discuss them without first choosing a label for themselves. APA: professional assessment ↗

What if life looks fine from the outside?

“Functioning addict” is sometimes used to describe someone who keeps up with work or other responsibilities while experiencing problems with substance use. For alcohol, NIAAA's clinical overview considers a wider pattern: control over drinking, health, relationships, and daily responsibilities. Our reading of that framework is that work performance alone cannot establish or rule out a disorder. “Functioning” is not one of its severity categories. NIAAA: clinical context ↗

02Understanding the difficulty

Why can stopping be difficult?

A person can want to stop drinking or using drugs and still find it difficult to stop. Psychologists Kent Berridge and Terry Robinson study a distinction that helps explain this: the motivation to use a substance can differ from the pleasure it brings.

Their research describes how reminders associated with drug use can increase the pull to use again, even when the experience has become less enjoyable. This is one scientific model, drawing on studies of people and animals. Berridge & Robinson, 2016 ↗

Explore the neuroscience

Three connected brain processes

NIAAA describes interacting systems involved in alcohol addiction. This simplified map follows that framework; it is not a brain scan or a test.

Select a process to explore its role.

Reward & learning

Alcohol-related cues can acquire motivational force through learning. Dopamine contributes to those associations. Circuits in the basal ganglia also help repeated actions become habits.

Stress & relief

During withdrawal, stress circuits involving the extended amygdala can become more active. Drinking again may be motivated by temporary relief from discomfort.

Planning & control

Heavy alcohol use can disrupt prefrontal systems involved in decisions and regulating behavior, making it harder to respond differently to urges.

These processes interact. They are not fixed steps that every person follows. NIAAA: framework and limits ↗

Three more pieces of the science

Adaptation: three terms with different meanings

Tolerance means a reduced response after repeated exposure, so more is needed for the same effect. Physical dependence means the body has adapted and withdrawal can occur when use stops. Addiction involves compulsive use despite harm. Physical dependence can occur with prescribed medication taken as directed; by itself, it does not establish addiction. NIDA: terminology ↗

Genetics: many influences, no single explanation

Many genes contribute to the risk of alcohol use disorder, usually through small individual effects. Environment also matters. This research concerns vulnerability; it does not identify one inevitable kind of person. NIAAA: genetics ↗

Sleep: falling asleep and sleeping well differ

A review by George Koob and Ian Colrain describes how alcohol can shorten the time it takes to fall asleep while worsening sleep quality and increasing wakefulness later in the night. It also examines persistent sleep disruption in alcohol use disorder. These findings do not make poor sleep a test for addiction. Koob & Colrain, 2020 ↗

What about shame?

Researchers also study emotions such as shame. A 2019 review found little overall relationship between shame and the amount of substances people used. It found a small association with substance-related problems. Studies following people over time produced mixed findings. Luoma and colleagues, 2019 ↗

Explore a finding

One review. Two different measures.

The results differ depending on what researchers measured: the amount used or the problems associated with use.

Full correlation range: −1 to +1
Association between shame and two substance-use measuresAmount of use: correlation 0.00, 95 percent confidence interval −0.05 to 0.06. Substance-related problems: correlation 0.16, interval 0.13 to 0.19. These associations do not establish cause.
Each dot is a pooled estimate; the line is its 95% confidence interval. Correlation describes an association, not cause.
Read the figures and study details
Shame review · author manuscript, pages 12–13
MeasureCorrelation95% intervalSamples / people
Amount of use0.00−0.05 to 0.0614 / 3,805
Related problems0.160.13 to 0.1918 / 5,250

Correlation runs from −1 to +1; zero indicates no linear association. These are separate evidence pools and may overlap. A correlation of 0.16 is not a percentage of people.

Open the review ↗ · Figures checked in the author manuscript.

03Family experience

What do families experience?

Family research looks at experiences beyond the person using a substance. These can include decisions about money and requests for help.

In a 2024 South African study, 15 relatives seeking support described living with people who used a drug known as nyaope. Participants reported repeated requests for money and theft. Some described giving money because they thought it might prevent further theft.

Because the researchers recruited a small group of relatives already seeking help, the findings cannot tell us how common these experiences are across all families affected by substance use. Nene and colleagues, 2024 ↗

04Meaning & belief

Where does faith fit?

Faith appears in some people's descriptions of change. At the 2026 Grammy Awards, Jelly Roll credited God and music with changing his life. That statement tells us how he describes his own experience. Le Monde, 2026 ↗

Christian scripture also addresses intention, conduct, and support. Romans 7 describes wanting to do good while acting against that intention. Galatians 6 discusses gentle restoration, helping with one another's burdens, and personal responsibility. Connecting these passages to addiction is an interpretation of religious texts. Romans 7 & Galatians 6 ↗

Personal testimony describes meaning in an individual's life. Research on recovery programs asks a different question: what outcomes do participants experience?

05Treatment & support

What support has evidence?

The National Institute on Drug Abuse describes addiction as treatable. Depending on the substance and the person's circumstances, care can include medication, behavioral therapies, and help with medical and social needs. A return to use can call for care to be resumed or adjusted. NIDA ↗

A 2020 Cochrane review examined Alcoholics Anonymous and treatments designed to help people participate in AA, known as twelve-step facilitation. Across the review, there were 27 studies and 10,565 participants with alcohol use disorder.

For structured programs, the comparison of continuous abstinence at one year favored AA and twelve-step facilitation over other established treatments. Several other outcomes were similar. The review did not establish religious belief as the reason for the benefit. Cochrane, 2020 ↗

A closer look at that comparison

The one-year result comes from two studies with 1,936 participants—not all 27 studies. Relative risk: 1.21, with a 95% confidence interval of 1.03–1.42. The review rated this comparison high certainty. This is a relative measure, not a 21-percentage-point increase.

06Life over time

What changes in recovery?

A 2018 U.S. survey asked adults who said they had resolved an alcohol or drug problem about their quality of life, happiness, self-esteem, and other aspects of well-being.

The researchers compared different people at one point in time. They did not follow the same individuals over the years, so the results cannot predict one person's experience or show that time alone produced the differences.

Among the people surveyed, those who reported more years in recovery generally reported better well-being. Kelly and colleagues, 2018 ↗

Can thinking skills improve?

A 2024 systematic review brought together 16 longitudinal studies of adults with alcohol use disorder. Many measured abilities—including aspects of attention, memory, and executive function—improved during abstinence, often reaching comparison levels within 6–12 months. Progress varied by ability and study. Powell and colleagues, 2024 ↗

That is evidence of room for improvement, not a deadline for an individual. Repeated-test practice, incomplete follow-up, and differences between studies limit the conclusions. The review does not show that every function recovers or that abstinence alone explains every change.

The evidence discussed here does not establish that everyone experiences the same struggle throughout their life.

Explore the sources

What can a source tell us?

Select a type of source to see what it contributes to this article.

Observed association

A pattern across studies

The shame review found different associations for the amount used and substance-related problems.

What it tells us

How the measured variables were related across the included samples.

What remains unanswered

Whether shame caused those outcomes, or what will happen to a particular person.

Luoma and colleagues, 2019 ↗

Personal account

How someone describes their life

Jelly Roll credited God and music with changing his life.

What it tells us

The meaning he gives his experience, as reported by Le Monde.

What remains unanswered

How faith affects recovery across people, or which treatment would help someone else.

Le Monde, 2026 ↗

Scripture

A religious account of human conduct

Romans 7 discusses conflict between intention and action.

What it tells us

How the passage describes that conflict within a theological discussion.

What remains unanswered

Its connection to addiction requires interpretation. It does not provide a clinical finding.

Romans 7:15–25 ↗

Intervention results

Outcomes after different kinds of support

The Cochrane review compared AA and twelve-step facilitation with other approaches.

What it tells us

The specified one-year abstinence comparison favored structured AA and twelve-step facilitation.

What remains unanswered

The comparison does not isolate religious belief as the cause of the result.

Cochrane, 2020 ↗

The reading behind this feature

Sources & notes

This feature draws on selected research, public reporting, and identified interpretations of scripture. It is a narrative overview, not a systematic review. Open a source for its scope and the material checked.

01Berridge & Robinson · Motivation and pleasure · 2016

Liking, Wanting, and the Incentive-Sensitization Theory of Addiction. Relevant passages: printed pages 671–673. A theoretical review of human and animal evidence; one model of addiction.

Read the source ↗
02Luoma, Chwyl & Kaplan · Shame review · 2019

Substance use and shame: A systematic and meta-analytic review. Numerical results checked in the author manuscript, pages 12–13; findings over time, page 29. The manuscript may differ from the final published version. Association does not establish direction.

Publication ↗ · Author manuscript ↗
03Nene and colleagues · Family interviews · 2024

Experiences of families living with Nyaope users in Tshwane, Gauteng province. Methods and interview passages checked on PDF pages 3–5; limitations on page 7. Fifteen selected, help-seeking relatives; no population prevalence estimate.

Read the study ↗
04Le Monde · Jelly Roll's Grammy remarks · 2026

Reporting dated 2 February 2026; relevant paragraph checked. His remarks are paraphrased as a dated personal account. The complete speech video was not reviewed.

Read the report ↗
05Romans 7 & Galatians 6 · Christian scripture

Passages checked in the New Revised Standard Version Updated Edition. Their relationship to addiction is an interpretation. Galatians is not presented as a direct saying of Jesus.

Romans 7:15–25 ↗ · Galatians 6:1–5 ↗
06NIDA · Treatment and recovery

Relevant sections of the official public health overview checked. Used for general background, not individualized advice. Page dated July 2020.

Read the overview ↗
07Kelly, Humphreys & Ferri · Cochrane review · 2020

Alcoholics Anonymous and other 12-step programs for alcohol use disorder. Publisher summary and abstract checked; the full review was not acquired. The comparison discussed here concerns standardized programs and adults with alcohol use disorder.

Read the summary and abstract ↗
08AP & Matthew Perry Foundation · Public context

AP's 3 November 2023 report establishes the foundation's launch after Perry's death. The foundation's homepage supplies its own mission statement; this is not a measured treatment outcome.

AP report ↗ · Foundation ↗
09Kelly, Greene & Bergman · Recovery and well-being · 2018

Beyond Abstinence. Abstract and figure captions checked; full methods not reviewed. A cross-sectional survey of U.S. adults reporting resolution of an alcohol or drug problem. It compares different people at one time.

Read the abstract ↗
10American Psychiatric Association · Substance use disorders

What Is a Substance Use Disorder? Opening definition, symptom categories, and the professional assessment paragraph under “How Is Substance Use Disorder Treated?” checked on 23 September 2026. Physician review dated April 2024. An institutional overview used to explain the subject, not assess readers.

Read the overview ↗
11NIDA & NIAAA · Risk factors and patterns

NIDA's Drug Misuse and Addiction: section on why risk differs between people. NIAAA's Alcohol Use Disorder: From Risk to Diagnosis to Recovery: symptoms and risk-factor sections. Checked on 23 September 2026. NIAAA's scope is alcohol. Control, Priority, and Impact are editorial teaching labels, not a diagnostic instrument; the example thoughts were written for this feature.

NIDA overview ↗ · NIAAA overview ↗
12Cleveland Clinic · The “addictive personality” label · 2023

What Does It Mean To Have an ‘Addictive Personality’? Published 19 April 2023. Opening explanation and “What is an addictive personality?” section checked on 23 September 2026. Used narrowly for the distinction between an informal expression and a psychiatric diagnosis. This is medical-center education, not a new empirical study or a personality test.

Read the explanation ↗
13NIAAA · Brain systems and recovery

Neuroscience: The Brain in Addiction and Recovery. Brain-change section and Figure 1 explanation checked on 23 September 2026. Institutional synthesis; the interactive map is an editorial simplification about alcohol.

Read the framework ↗
14NIDA · Dependence and addiction · 2018 revision

Principles of Drug Addiction Treatment: A Research-Based Guide, third edition, revised January 2018. PDF page 17, “Is there a difference between physical dependence and addiction?” checked. Used only for this terminology distinction, not current treatment recommendations.

Read the PDF passage ↗
15NIAAA · Genetics and alcohol use disorder

Health Topics: Genetics and Alcohol Use Disorder. “At a Glance” checked on 23 September 2026. Institutional overview; no personal genetic prediction is offered.

Read the overview ↗
16Koob & Colrain · Alcohol and sleep · 2020

Alcohol use disorder and sleep disturbances: a feed-forward allostatic framework. Online 24 June 2019; 2020 journal issue. Abstract checked through PubMed; full text not reviewed. The proposed feedback framework is not evidence that treating sleep alone treats addiction.

Read the abstract ↗
17Powell and colleagues · Thinking skills in recovery · 2024

Recovery of neuropsychological function following abstinence from alcohol in adults diagnosed with an alcohol use disorder. Methods, results, and “Robustness of synthesis” checked in the open-access article. Sixteen studies in the synthesis; adults aged 18–64; searches updated March 2023. Comparison-level test performance does not mean every aspect of recovery is complete.

Read the review ↗

No original interviews were conducted. The fictional examples and brain-process map are editorial illustrations. Much of the added neuroscience concerns alcohol; it should not be assumed to describe every substance or behavior in the same way.